downstream sequence

Conclusion Our data suggest that antisense ODNs complementary to the initiation codon of IGF-IR mRNA and its downstream sequence can effectively prevent the translation of the target mRNA into protein product , thus block or weaken the expression of IGF-IR .

结论针对IGF-IR基因mRNA序列起始密码子及下游序列所设计的反义寡核苷酸能有效阻止mRNA的翻译功能，使其蛋白产物表达下调，达到封闭或减弱该基因表达的目的。

Effect of Downstream Sequence on the Cleavage of Envelop Protein 1 Signal Sequence in Hepatitis C Virus

丙型肝炎病毒被膜蛋白E1信号序列的切割受下游序列的影响

As both flavivirus and HCV are classified into the same Flaviviridae family , this downstream sequence related cleavage of signal sequence worths further studying .

由于黄病毒和HCV均属黄病毒科，这种在同一科内具有相类似的异常的信号序列加工，其生物学意义值得深入研究。

We suppose that the following causes lead to the occurrence of ? R6 . First , one end of mutant was inserted into genome DNA because of the homologous recombination mediated by downstream homologous sequence .

我们推测，出现该突变株的原因可能有：①下游同源臂发生预期的同源重组，导致突变子的一端嵌入基因组。